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Torque Teno Virus

rendering of heart and lungs in the body

What is Torque Teno Virus? (TTV)


Common references for Torque Teno Viruses Include:

Singla A, Chen K, Robelly B, Rebello C, Lantz C, Zhao L, Sinha R, Park S, Kleiboeker S, Friedewald JJ, Mehrotra S. Using Torque Teno Virus as a Serial Monitoring Tool for the Net State of Immunosuppression of Kidney Transplant Recipients. Clin Transplant. 2025 Sep;39(9):e70321. doi: 10.1111/ctr.70321. PMID: 40965933.

Fishman JA. Infection in Organ Transplantation. Am J Transplant. 2017 Apr;17(4):856-879. doi: 10.1111/ajt.14208. Epub 2017 Mar 10. PMID: 28117944.Görzer I et al. Journal of Clinical Virology 2023; 158:105384. doi: 10.1016/j.jcv.2022.105348

Sinha R, Zhu Z, Park S, Rebello C, Kinsella B, Friedewald J, Kleiboeker S. Combined Metagenomic Viral Detection and Donor-Derived Cell-Free DNA Quantification in Plasma From Kidney Transplant Recipients. Transplant Proc. 2024 Jul-Aug;56(6):1522-1530. doi: 10.1016/j.transproceed.2024.06.003. Epub 2024 Jul 6. PMID: 38972761.

van Rijn AL, Roos R, Dekker FW, Rotmans JI, Feltkamp M. Torque teno virus load as marker of rejection and infection in solid organ transplantation – A systematic review and meta-analysis. Rev Med Virol. 2023 Jan;33(1):e2393. doi: 10.1002/rmv.2393. Epub 2022 Sep 3. PMID: 36056751; PMCID: PMC10078304.

Doberer K, Schiemann M, Strassl R, Haupenthal F, Dermuth F, Görzer I, Eskandary F, Reindl-Schwaighofer R, Kikić Ž, Puchhammer-Stöckl E, Böhmig GA, Bond G. Torque teno virus for risk stratification of graft rejection and infection in kidney transplant recipients-A prospective observational trial. Am J Transplant. 2020 Aug;20(8):2081-2090. doi: 10.1111/ajt.15810. Epub 2020 Mar 8. PMID: 32034850; PMCID: PMC7496119.

Irene Görzer, Frederik Haupenthal, Fabrizio Maggi, Fanny Gelas, Dorian Kulifaj, Ludovic Brossault, Elisabeth Puchhammer-Stöckl, Gregor Bond, Validation of plasma Torque Teno viral load applying a CE-certified PCR for risk stratification of rejection and infection post kidney transplantation, Journal of Clinical Virology, Volume 158, 2023, 105348, ISSN 1386-6532,